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A delicious slice of high-protein cottage cheese lasagna on a plate, showing layers of pasta, sauce, and melted cheese.

High-Protein Cottage Cheese Lasagna

Avatar photoAmelia Chen-Morrison
This High-Protein Cottage Cheese Lasagna redefines comfort food by using blended cottage cheese for an unbelievably creamy, protein-packed filling. Perfectly cooked noodles cradle a rich, savory meat sauce and a velvety cheese layer, creating a satisfying and light yet deeply comforting meal.
Prep Time 30 minutes
Cook Time 1 hour 30 minutes
Total Time 2 hours
Course Main Course
Cuisine Italian-American
Servings 8
Calories 550 kcal

Equipment

  • 9x13 inch baking dish
  • Large Dutch oven or heavy-bottomed pot
  • Food processor or blender
  • Aluminum foil
  • Wire cooling rack
  • Large spoon or spatula
  • Measuring cups and spoons
  • Knife
  • Cutting board

Ingredients
  

  • 1 tablespoon olive oil
  • 1 lb lean ground beef 90/10 or 93/7
  • 1 medium yellow onion, chopped
  • 4 cloves garlic, minced
  • 2 tablespoons tomato paste
  • 2 teaspoons Italian seasoning
  • 1 teaspoon salt, plus more to taste
  • ½ teaspoon black pepper, plus more to taste
  • ½ cup grated Parmesan cheese
  • 1 large egg
  • ¼ cup fresh parsley, chopped
  • 12 lasagna noodles standard or no-boil
  • 3 cups shredded low-moisture, whole milk mozzarella cheese

Instructions
 

  • To make the meat sauce, heat olive oil in a large Dutch oven over medium-high heat. Add the ground beef and cook, breaking it apart, until browned. Drain any excess fat. Add the chopped onion and cook for 4-5 minutes until softened. Stir in the minced garlic and cook for 1 more minute until fragrant.
  • Stir in the tomato paste and cook for 1 minute. Pour in the crushed tomatoes, Italian seasoning, salt, and pepper. Bring to a simmer, then reduce heat to low, cover, and let it simmer for at least 30 minutes to allow flavors to meld.
  • While the sauce simmers, prepare the cheese filling. In a food processor or blender, combine the full-fat cottage cheese, grated Parmesan cheese, egg, and fresh parsley. Blend on high for 30-60 seconds until completely smooth and creamy.
  • Preheat your oven to 375°F (190°C). Begin assembling the lasagna in a 9x13 inch baking dish. Spread a thin layer of meat sauce on the bottom of the dish.
  • Arrange a single layer of lasagna noodles over the sauce. Spread half of the creamy cottage cheese mixture over the noodles. Top with one-third of the remaining meat sauce, then sprinkle with one-third (1 cup) of the shredded mozzarella.
  • Repeat the layers: another layer of noodles, the rest of the cottage cheese mixture, another third of the meat sauce, and another third (1 cup) of the mozzarella.
  • Finish with a final layer of noodles, the last of the meat sauce, and the remaining one-third (1 cup) of mozzarella cheese on top.
  • Cover the baking dish tightly with aluminum foil. Bake in the preheated oven for 40 minutes.
  • After 40 minutes, carefully remove the foil. Return the lasagna to the oven and bake uncovered for another 15-20 minutes, until the top is golden brown and the sauce is bubbling.
  • This is a crucial step: Let the lasagna rest on a wire rack for at least 15-20 minutes before slicing and serving. This allows the layers to set for clean, perfect slices.

Notes

For best results, use full-fat cottage cheese to ensure a creamy, not watery, filling. If using standard lasagna noodles that require boiling, undercook them by 2-3 minutes as they will finish cooking in the oven. For variations, try substituting ground beef with Italian sausage, adding a layer of sautéed spinach, or mixing a few tablespoons of softened cream cheese into the cottage cheese filling for extra richness. Store leftovers in an airtight container in the refrigerator for up to 4 days.